Sheng Chen, M.D.
Joined PACI in 2017.

Board Certified by the American Board of pathology in Clinical and Anatomic Pathology

Subspecialty certification:

• Dermatopathology

Areas of Special Interest :

• Surgical pathology

• Dermatopathology

Dr. Chen received his medical degree from Xiangya Medical School (previously Hunan Medical University), Changsha, Hunan, China and his Ph.D. degree in neuroscience from Drexel School of Medicine (previously MCP-Hahnemann University), Philadelphia, PA. He completed his residency training in pathology at Long Island Jewish Medical Center, New Hyde Park, NY, under the directorship of Dr. Leonard B. Kahn, and a dermatopathology fellowship under the directorship of the late Dr. Bernard Ackerman at Ackerman Academy of Dermatopathology, New York. Before joining PACI in 2017, Dr. Chen worked as staff pathologist/dermatopathologist and then as Chief of Dermatopathology at the Department of Pathology & Laboratory Medicine and Department of Dermatology, Hofstra Northwell School of Medicine for many years. He is board certified in clinical & anatomic pathology and dermatopathology. He is a member of American Society of Dermatopathology, International Society of Dermatopathology, and College of American Pathologists, the Editorial Board of the journal Dermatology Practical & Conceptual. His main interest is in tumor biology, melanocytic lesions and skin adnexal neoplasms.

Publications:

• Chen S and Su H-S. The origin of noradrenergic fibers in the septum of the rat - a study of combined retrograde fluorescent labeling and histofluorescence. Acta Anatomica Sinica (Chinese), 19(1988):381-385.

• Chen S and Su H-S. Selective labeling by propidium iodide injected into the lateral cerebral ventricle of the rat. Brain Res. 483(1989):379-383.

• Chen S and Su H-S. The afferent connections of the thalamic paraventricular and parataenial nuclei in the rat - a retrograde tracing study with iontophoretic application of Fluoro-Gold. Brain Res. 522(1990):1-6.

• Chen S, Raos V and Bentivoglio M. Connections of the thalamic reticular nucleus with the contralateral thalamus in the rat. Neurosci. Lett. 147(1992):85-88.

• Chen S and Bentivoglio M. Nerve growth factor receptor-containing cholinergic neurons of the basal forebrain project to the thalamic reticular nucleus in the rat. Brain Res. 606(1993):207-212.

• Chen S, Peng Z-C and Bertini G. Neural substrate of a cerebellar movement disorder induced by intracerebroventricular injection of propidium iodide in the rat: a Fos immunocytochemical study. Exp. Neurol. 125(1994):72-81.

• Peng Z-C, Chen S, Fusco M, Vantini G and Bentivoglio M. Fos induction by nerve growth factor in the adult rat brain. Brain Res. 632(1993):57-67.

• Chen S and Aston-Jones G. Cerebellar injury induces NADPH diaphorase in Purkinje and inferior olivary neurons in the rat. Exp. Neurol. 126(1994):270-76.

• Chen S and Aston-Jones G. Evidence that cholera toxin B subunit (CTb) can be avidly taken up and transported by fibers of passage. Brain Res. 674(1995):107-111.

• Chen S and Aston-Jones G. Anatomical evidence for inputs to ventrolateral medullary catecholaminergic neurons from the midbrain periaqueductal gray of the rat. Neurosci. Lett. 195(1995):140-144.

• Chen S and Aston-Jones G. Extensive projections from the midbrain periaqueductal gray to the caudal ventrolateral medulla: a retrograde and anterograde tracing study in the rat. Neuroscience 71(1996):443-459.

• Tassinari G, Bentivoglio M, Chen S and Campara D. Overlapping ipsilateral and contralateral retinal projections to the lateral geniculate nucleus and superior colliculus in the cat: a retrograde triple labelling study. Brain Res. Bull. 43(1997):127-139.

• Chen S and Aston-Jones G. Axonal collateral-collateral transport of tract tracers in brain neurons: false anterograde labeling and useful tool. Neuroscience 82(1997):1151-1163.

• Chen S, Yang M, Miselis RR and Aston-Jones G. Methodological characterization of transsynaptic tracing with pseudorabies virus following injections into the rat brain. Brain Res, 838(1999):171-183.

• Aston-Jones G, Chen S, Zhu Y and Oshinsky M. A neural circuit for circadian regulation of arousal. Nat Neurosci, 4(2001):732-738.

• Chen S, Bhuiya T, Liatsikos EN, Alexianu MD, Weiss GH and Kahn LB. Primary synovial sarcoma of the kidney: a case report with literature review. Int J Surg Pathol, 9(2001):335-339.

• Savargaonkar P, Chen S, Bhuiya T, Valderama E, Bloom T, Farmer PM. Meningioangiomatosis: report of three cases and review of the literature. Ann Clin Lab Sci, 33:115-8, 2003.

• Chen S. New Quandary: Diffuse neuroendocrine system? Dermatopathol: Pract & Conc, 9(3), 2003. Available at: http://www.derm101.com.

• Chen S and Ackerman AB. Patterns of epithelial and non-epithelial elements in skin. Dermatopathol: Pract & Conc, 9(4), 2003. Available at: http://www.derm101.com.

• White S and Chen S. What is “pigmented epithelioid melanocytoma?” Am J Surg Pathol, 29:1118, 2005.

• Patel K, Bhuiya T, Chen S, Kena S and Kahn L. Epidermal inclusion cyst of phalanx: a case report and review of the literature. Skeletal Radiol, 35:861-3, 2006.

• Gao JZ and Chen S. Post-radiation angiosarcoma of the skin featuring capillary lobules. Am J Dermatopathol, 28:376, 2006.

• Ouansafi I and Chen S. So called “de novo intraepidermal epithelioid melanocytic dysplasia” is melanoma in situ. J Cutan Pathol, 34:811, 2007.

• Gao ZQ, Palleschi SM, Chen S. Plexiform epithelioid schwannoma: a case report. Am J Dermatopathol, 29:56-8, 2007.

• Gao ZQ, Stanek A, Chen S. A metastatic melanoma with unusual immunophenotypic profile. Am J Dermatopathol, 29:169-71, 2007

• Macias A, Chen, S. Quiz: a 32-year-old man with a skin nodule (indeterminate cell histiocytosis). Dermatopathol: Pract & Conc, 13(1): 13, 2007. Available at: http://www.derm101.com.

• Asgari M and Chen S. What is the true nature of colonic adenoma? Part I: Confusion and controversy – a historical literature review. Dermatopathol: Pract & Conc, 13(3): 7, 2007. Available at: http://www.derm101.com.

• Asgari M and Chen S. What is the true nature of colonic adenoma? Part II: Confusion and controversy continued – a contemporary literature review. Dermatopathol: Pract & Conc, 13(4): 8, 2007. Available at: http://www.derm101.com.

• Asgari M, Chen S. What is the true nature of colonic adenoma? Part III: It is carcinoma in situ: a histopathology reassessment. Dermatopathol: Pract & Conc, 14(2): 4, 2008. Available at: http://www.derm101.com.

• Chan KC, Freedman AM, Chen S. Spitz nevus versus melanoma: a mitotically active epithelioid melanoctytic neoplasm. Dermatopathol: Pract & Conc, 14(2): 10, 2008. Available at: http://www.derm101.com.

• Goyal A, Chen S. Bronchioloalveolar carcinoma is really carcinoma in situ. Arch Pathol Lab Med, 132:1548, 2008.

• Arefi M, Philipone E, Caprioli R, Haight J, Richardson H, Chen S. A case of verrucous carcinoma (epithelioma cuniculatum) of the heel mimicking infected epidermal cyst and gout. Foot Ankle Spec, 1(5):297-9, 2008.

• Asgari M, Chen S. What is the true nature of colonic adenoma? Part IV: It is carcinoma in situ - a concept further supported via comparison with carcinoma in situ of the skin and of the breast. Dermatopathol: Pract & Conc, 15(1): 4, 2009. Available at: http://www.derm101.com.

• Chen S, Asgari M. Controversies: Dysplasia in colorectal adenomas. Dermatopathol: Pract & Conc, 15(4):8, 2009. Available at: http://www.derm101.com.

• Franklin G, Chen S, Sznyter LA, Morgenstern N. Cutaneous myoepithelioma with a plexiform pattern of growth: a case report. J Cutan Pathol, 36(Suppl 1): 42-5, 2009.

• Philipone E, Chen S. Unique case: syringocystadenoma papilliferum associated with an eccrine nevus. Am J Dermatopathol, 31:806-7, 2009.

• Franklin G, Greenspan J, Chen S. Anti-tumor Necrosis Factor-alpha Therapy Provokes Latent Leishmaniasis Infection in a Patient with Rheumatoid Arthritis: A case report. Ann Clin Lab Sci, 39:192-5, 2009.

• Chen S. A different view: Sebaceous adenoma is sebaceous carcinoma in situ. Dermatopathol: Pract & Conc, 16(2):16, 2010. Available at: http://www.derm101.com.

• Chen S. The dysplastic nevus controversy: It is not about the nevus per se but one's belief in the multistep tumorigenesis theory. Am J Dermatopathol, 32:858, 2010.

• Kramer J, Chen S. Sebaceous carcinoma in situ. Am J Dermatopathol, 32:854-5, 2010.

• Reddy K, Hoda S, Penstein A, Wasil T, Chen S. Bullous amyloidosis complicated by cellulitis and sepsis: a case report. Arch Dermatol, 147:126-7, 2011.

• Rishi A, Dulanto F, Chen S. Glomangiosarcoma in the shoulder of 51 years old man. Dermatol Pract Concept, 2(2), 2012.

• Klingman DE, Chen S. Infundibular squamous cell carcinoma: a new entity? Am J Dermatopathol, 34(6):676-7, 2012.

• Madan R, Chen S. Editorial: The so-called dysplastic nevus is not dysplastic at all. Dermatol Pract Concept, 3(1):1, 2013.

• Asgari M, Chen S. Papillary eccrine adenoma should not be mistaken for aggressive digital papillary adenocarcinoma. Clin Exp Dermatol, 39(2): 223-4, 2014.

• Chen S, Asgari M. Papillary Adenocarcinoma in situ of the skin: report of four cases. Dermatol Pract Concept, 4(2): 23-8, 2014.

• Chen S, Asgari M. Editorial: Is aggressive digital papillary adenocarcinoma really aggressive digital papillary adenocarcinoma? Dermatol Pract Concept, 4(3): 33-5, 2014.

• Vitkovski T, Costales C, Chen S, Saltman B, Kahn L. Malakoplakia of the thyroid gland: a case report and review of literature. Int J Surg Pathol. 23(4):308-12, 2015.

• Navale P, Asgari M, Chen S. Pigmented perivascular epithelioid cell tumor of the skin: first case report. Am J Dermatopathol. 37(11):866-9, 2015

• Derrington SM, Cellura AP, McDermott LE, Gubitosi T, Sonstegard AM, Chen S, Garg A. Mucocutaneous Findings and Course in an Adult With Zika Virus Infection. JAMA Dermatol. 152(6):691-3, 2016.

• Rafael O, Paul D, Chen S and Kraus D. Adenoid cystic carcinoma of submandibular gland metastatic to great toes: case report and literature review. Clinical Case Reports. 4(8):820-3, 2016

• Chen J, Beg M and Chen S. Syringocystadenocarcinoma papilliferum in situ, a variant of cutaneous adenocarcinoma in situ: a case report with literature review. Am J Dermatopathol. 38(10):762-5, 2016.

• Komforti MK, Asgari M, Chen S. Sebaceous carcinoma in situ as a concept and diagnostic entity. Dermatol Pract Concept, 7(3):5, 2017. DOI: https://doi.org/10.5826/dpc.0703a05

• Asgari M, Chen S. Cutaneous papillary adenocarcinoma in situ. J Cutan Pathol. 44:410-1, 2017.

• Shergill U, Asgari M, Chen S. The so-called aggressive digital papillary adenocarcinoma is epithelial-myoepithelial carcinoma. Am J Dermatopathol. 40(2): 152, 2018.

• Cellura AP, Gallitano SM, McDermott LE, Shantharam R, Finelt N, Chen S. Kikuchi-Fujimoto disease in a teenage boy: a case report with literature review. Cutis. 2018, in press.